Figure 8.

Impact of lower alignment quality. Examples of ROCS versus AR-0.73 alignments from Figure 7. Left side: Query (yellow), ROCS alignment (dark blue) and AR alignment (cyan). Right side: Same as left side but with query removed.A) AR shape Tanimoto 0.01 worse than ROCS. B) AR shape Tanimoto 0.03 worse than ROCS. C) AR shape Tanimoto 0.05 worse than ROCS.